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by: Paris (AFP)<\/p>\n
<\/p>\n
One in almost 3,000 blood donors in England carry the hepatitis E virus (HEV) which can cause liver disease, said a study Monday that sparked a call for screening in Europe.<\/p>\n
Published on World Hepatitis Day, a study in The Lancet medical journal said a systematic analysis of donated blood showed that 79 out of 225,000 donations were infected with a version of the virus, genotype 3, most prevalent in developed countries.<\/p>\n
Humans can contract it from infected pigs and contaminated blood or drinking water.<\/p>\n
Transmission of the virus had occurred in 18 of 43 exposed blood recipients, the authors said.<\/p>\n
One developed mild clinical hepatitis.<\/p>\n
“HEV genotype 3 infections are widespread in the English population, including blood donors,” said principal investigator Richard Tedder from the Blood Borne Virus Unit at Public Health England.<\/p>\n
“We estimate that between 80,000 and 100,000 human HEV infections are likely to have occurred in England during the year of our study.”<\/p>\n
Similar prevalences had previously been reported in Sweden in Germany, suggesting the virus was widespread on the European continent, said the study.<\/p>\n
Most people who contract the virus recover from symptoms including appetite loss and fever without treatment, but it can be dangerous for those with a suppressed immune systems, like cancer patients and organ transplant recipients, as well as pregnant women.<\/p>\n
There is no cure.<\/p>\n
The study authors said the overall risk was slight, and “there appears to be no pressing need at this time for blood donations to be screened.”<\/p>\n
In a comment carried by The Lancet, however, Jean-Michel Pawlotsky from the Henri Mondor hospital in Paris, said this conclusion was “surprising”.<\/p>\n
On his own reading of the results, “systematic screening of blood components for markers of hepatitis E infection should be implemented in areas where HEV is endemic” — including the European Union.<\/p>\n
Two other papers carried by the journal reported successes in trials with two pill-form antiviral drugs in treating hepatitis C, a blood-borne liver disease that affects about 150 million people worldwide and is often transmitted through needle-sharing.<\/p>\n
It is a major cause of liver failure and cancer.<\/p>\n
The two drug regimens hold promise for a safer, shorter and simpler cure, said the papers — one took only 12 weeks to work compared to older injection-pill combination treatments that could last up to a year.<\/p>\n
“In the future, very-short-duration, all-oral (antivirals) should improve treatment uptake and success,” Ed Gane, director of the New Zealand Liver Transplant Unit at Auckland City Hospital wrote in a comment.<\/p>\n
The only barrier to achieving this goal would be the cost of treatment, he added.<\/p>\n","protected":false},"excerpt":{"rendered":"
by: Paris (AFP) One in almost 3,000 blood donors in England carry the hepatitis E virus (HEV) which can cause liver disease, said a study Monday that sparked a call for screening in Europe. Published on World Hepatitis Day,…<\/span><\/p>\n